降脂通脉冲剂对实验性高脂血症大鼠血浆脂质及血粘度的影响

被引：10

作者：

李春梅

刘莉

机构：

[1] 山西医科大学病生理学教研室!太原

[2] 山西医科大学实验管理科

来源：

山西医科大学学报 | 2000年 / 01期

关键词：

降血脂药; 降脂通脉冲剂; 高脂血症; 血液粘度; 大鼠;

D O I：

暂无

中图分类号：

R285 [中药药理学];

学科分类号：

摘要：

采用高脂饲料喂养大鼠 4周造成高脂血症模型 ,观察降脂通脉冲剂对血脂和血粘度的影响。降脂通脉冲剂 1 1～ 2 2g/kg灌胃 ,可抑制血清总胆固醇 (TC)低密度脂蛋白胆固醇 (LDL -c)甘油三酯 (TG)和致动脉硬化指数 (AI)而升高高密度脂蛋白胆固醇 (HDL -c)和抗动脉硬化指数 (AAI)。降脂通脉冲剂亦可降低高脂血症大鼠的血浆粘度和高切变率 ( 2 3 0s-1)、低切变率 ( 5 5 7s-1)下的全血粘度 ,但对红细胞聚集指数 (RBCAI)则无明显影响。可见降脂通脉冲剂具有抗高血脂和高血粘作用

引用

页码：22 / 23

页数：2

共 8 条

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