利用体内探针法考察植物药和天然产物对人体细胞色素P450和P-糖蛋白活性的影响

被引:4
作者
叶蓁
朱玲玲
周权
机构
[1] 浙江大学医学院附属第二医院
关键词
植物药; 细胞色素P450; P-糖蛋白; 体内探针法;
D O I
暂无
中图分类号
R963 [生化药理学];
学科分类号
100706 [药理学];
摘要
目的促进植物药和天然产物对人体细胞色素P450和P-糖蛋白活性影响的人体研究的深入,预期临床相互作用,提高合理用药水平。方法综述体内探针法在该领域的国内外的应用。详细介绍应用方法和注意事项。结果国外利用体内探针法的研究较热。鸡尾酒探针法的应用已成熟。结论在我国应大力支持和推广体内探针法在新药研发和临床应用中的研究。
引用
收藏
页码:596 / 603
页数:8
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