原发性肝癌手术切除后的肝功能变化及其处理

被引:2
作者
周信达 [1 ]
汤钊猷 [1 ]
余业勤 [1 ]
机构
[1] 上海第一医学院中山医院肝癌研究室
关键词
D O I
暂无
中图分类号
R735 [消化系肿瘤];
学科分类号
100214 ;
摘要
本文报道上海第一医学院中山医院1965~1978年间70例原发性肝癌手术切除后的肝功能变化及其处理。术后谷丙转氨酶和碱性磷酸酶显著升高,数天后恢复正常。血清胆红质(特别是直接胆红质)在术后6~10天出现潴留现象,嗣后逐渐下降,1个月后恢复术前值。血清总蛋白下降,特别是白蛋白术后第1天即开始下降,持续1~2个月。球蛋白在1周内下降,随后又升高,白蛋白和球蛋白的比例缩小或倒置。根治性切除术后一般在1个月内甲胎蛋白对流免疫电泳法转阴(<500毫微克/毫升),2个月内放射免疫法转阴(<20毫微克/毫升)。肝切除量、有无合并肝硬变及术前肝功能状况是影响术后代谢变化的主要因素。术后保肝治疗对促进肝功能恢复具有重要意义,除补充维生素K、B、C和抗菌素外,特别要及早补充足够的能量和蛋白质。
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