E-钙粘蛋白与肺癌侵袭转移

被引:9
作者
罗金明 [1 ]
陈少贤 [2 ]
机构
[1] 浙江台州市第一人民医院
[2] 温州医学院附属第一人民医院呼吸内科
关键词
E-钙粘蛋白; 肿瘤转移; 肺癌; 预后;
D O I
暂无
中图分类号
R734.2 [肺肿瘤];
学科分类号
100117 [系统生物医学];
摘要
E-钙粘蛋白(E-cadherin,E-cad)是一类介导细胞与细胞间相互黏附、具有维持组织结构完整性和极性的钙依赖性跨膜糖蛋白。较多研究证实E-cad与多种上皮恶性肿瘤的分化、侵袭、转移和预后相关。本文就E-cad的结构功能、在肿瘤侵袭转移中的作用机制、与肺癌的关系及血清可溶性E-cad检测的临床意义作一综述。
引用
收藏
页码:441 / 444
页数:4
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