锌在儿童腹泻治疗中的作用

被引:17
作者
应爱娟
江米足
机构
[1] 浙江大学医学院附属儿童医院
关键词
锌; 腹泻; 儿童;
D O I
暂无
中图分类号
R725.7 [小儿消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
锌参与维持离子通道和生物膜的完整性,参与酶的合成与激活,促进生长发育和创伤愈合,是体内重要的微量元素。腹泻时由于摄入减少、小肠吸收不良、胃肠道丢失增多等可引起血锌的降低,而肠黏膜再生需要的锌可因此缺乏或不足,导致病情迁延。补锌能加速肠黏膜再生,增加刷状缘酶水平,增强机体细胞免疫和体液免疫功能,提高肠黏膜的抗病能力。研究表明,锌能治疗和预防腹泻,世界卫生组织已向全球推荐5岁以下急性或慢性腹泻患儿每天口服10~20mg锌,持续10~14d。但对于补锌的年龄和剂量尚有争论。
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