全凭静脉麻醉妇科腹腔镜术后恶心呕吐的临床观察

被引：14

作者：

耿志宇

胡晓

机构：

[1] 北京大学第一医院麻醉科

来源：

中国微创外科杂志 | 2009年 / 10期

关键词：

术后恶心呕吐; 麻醉; 静脉; 手术; 腹腔镜;

D O I：

暂无

中图分类号：

R614 [麻醉学];

学科分类号：

100217 [麻醉学];

摘要：

目的观察妇科腹腔镜手术患者丙泊酚全凭静脉麻醉(TIVA)术后恶心呕吐的发生率。方法138例妇科腹腔镜手术随机分为七氟烷(Sev)组、七氟烷-恩丹西酮(Sev-O)组及丙泊酚TIVA组,每组46例。Sev组和Sev-O组:术中以持续吸入50%N2O和七氟烷维持麻醉,Sev-O组手术结束前30min静脉给予恩丹西酮8mg;TIVA组:术中以丙泊酚、瑞芬太尼靶控输注维持麻醉。记录术后24h内发生恶心呕吐及额外需要止吐药情况。结果TIVA组术后0～2h恶心呕吐发生率[22%(10/46)]低于Sev组[54%(25/46),χ2=10.376,P=0.001]和Sev-O组[50%(23/46),χ2=7.986,P=0.005]。Sev-O组术后2～6h恶心呕吐发生率低于Sev组[22%(10/46)vs46%(21/46),χ2=5.887,P=0.015]。TIVA组术后0～24h恶心呕吐发生率低于Sev组[57%(26/46)vs80%(37/46),χ2=6.093,P=0.014)。3组分别有13例(28%)、6例(13%)、6例(13%)术后需要额外止吐药。结论与七氟烷吸入麻醉比较,丙泊酚全凭静脉麻醉可降低妇科腹腔镜手术后恶心呕吐的发生率。

引用

页码：892 / 895

页数：4

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