放射性肺炎相关预测指标的研究进展

被引：23

作者：

李双双 ^{[1
]}

孔炜伟 ^{[2
]}

刘宝瑞 ^{[2
]}

机构：

[1] 南京大学医学院

[2] 南京大学医学院附属鼓楼医院肿瘤中心,南京大学临床肿瘤研究所

来源：

现代肿瘤医学 | 2015年 / 23卷 / 08期

关键词：

放射性肺炎; 剂量学参数; 肺功能; 生物标志物; 临床参数;

D O I：

暂无

中图分类号：

R734 [呼吸系肿瘤];

学科分类号：

100117 [系统生物医学];

摘要：

放射性肺损伤(radiation-induced lung toxicity,RILT)是胸部肿瘤患者放射治疗的主要副反应之一,亦是影响放射治疗疗效的主要剂量限制性因素。RILT包括放射性肺炎(radiation pneumonitis,RP)和放射性肺纤维化(radiation fibrosis,RF)。放射性肺炎通常发生于放疗开始后的1-6个月。放射性肺纤维化的发生较缓慢通常为数月到几年之间。本综述就与放射性肺炎有关的临床和剂量学等参数进行分析,旨在提供临床可行的预测指标,以指导肺癌放射治疗计划的制订,减少正常组织的放射性损伤。

引用

页码：1152 / 1156

页数：5

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