中西药促胃肠动力药治疗慢传输型便秘的临床研究进展

被引:44
作者
杨稀
杨勇军
刘仕鸿
李钟艳
刘畅
机构
[1] 川北医学院附属医院肛肠科
关键词
促胃肠动力药; 中药; 便秘; 研究进展;
D O I
暂无
中图分类号
R574.62 [结肠疾病];
学科分类号
100201 [内科学];
摘要
促胃肠动力药种类很多,根据其不同的作用机制,广泛应用于各种胃肠动力减弱的疾病。其对便秘的治疗研究逐渐增多,中西药促胃肠动力药物通过不同环节调节胃肠道平滑肌的运动,抑制胃肠逆蠕动,恢复胃肠正常蠕动,改善便秘症状。但各种西药促动力药物在临床应用中均被发现有不同程度的不良反应,如何研究一种安全、有效、价廉的促胃肠动力药物治疗慢性功能性便秘有很重要的临床价值。
引用
收藏
页码:546 / 551
页数:6
相关论文
共 39 条
[1]
四逆散的促胃肠动力作用及毒理研究 [D]. 
罗丹 .
吉林大学,
2008
[2]
Systematic review with meta-analysis: highly selective 5-HT4 agonists (prucalopride, velusetrag or naronapride) in chronic constipation [J].
Shin, A. ;
Camilleri, M. ;
Kolar, G. ;
Erwin, P. ;
West, C. P. ;
Murad, M. H. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2014, 39 (03) :239-253
[3]
Effect of prucalopride on symptoms of chronic constipation [J].
Tack, J. ;
Stanghellini, V. ;
Dubois, D. ;
Joseph, A. ;
Vandeplassche, L. ;
Kerstens, R. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2014, 26 (01) :21-27
[4]
Prucalopride: A Review of Its Use in the Management of Chronic Constipation [J].
Keating, Gillian M. .
DRUGS, 2013, 73 (17) :1935-1950
[5]
Oral Prucalopride in Children With Functional Constipation [J].
Winter, Harland S. ;
Di Lorenzo, Carlo ;
Benninga, Marc A. ;
Gilger, Mark A. ;
Kearns, Gregory L. ;
Hyman, Paul E. ;
Vandeplassche, Lieve ;
Ausma, Jannie ;
Hoppenbrouwers, Mieke .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2013, 57 (02) :197-203
[6]
Effect of intravenous erythromycin on the colonic motility of children and young adults during colonic manometry [J].
Dranove, Jason ;
Horn, Debra ;
Reddy, S. Narasimha ;
Croffie, Joseph .
JOURNAL OF PEDIATRIC SURGERY, 2010, 45 (04) :777-783
[7]
Electrophysiological Characterization of Isolated Human Atrial Myocytes Exposed to Tegaserod [J].
Suffredini, Silvia ;
Cerbai, Elisabetta ;
Giunti, Gabriele ;
El Mouelhi, Mohamed ;
Pfannkuche, Hans-Juergen ;
Mugelli, Alessadro .
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2010, 106 (05) :416-421
[8]
Tegaserod; a 5‐HT<sub>4</sub> receptor partial agonist; relieves symptoms in irritable bowel syndrome patients with abdominal pain; bloating and constipation.[J].S. A. Müller‐Lissner;I. Fumagalli;K. D. Bardhan;F. Pace;E. Pecher;B. Nault;P. Rüegg.Alimentary Pharmacology & Therapeutics.2001, 10
[9]
The effect of mosapride citrate on proximal and distal colonic motor function in the guinea‐pig in vitro.[J].H. S.Kim;E. J.Choi;H.Park.Neurogastroenterology & Motility.2007, 2
[10]
Efficacy of tegaserod for functional constipation in Chinese subjects: a randomized double‐blind controlled trial in a single centre.[J].A. O.ON CHAN;W.MO HUI;G.LEUNG;W. H. C.HU;S. K.LAM;B. C. Y.WONG.Alimentary Pharmacology & Therapeutics.2006, 4