飞行时间质谱技术鉴定丝状真菌的研究进展

被引:5
作者
张敬霞 [1 ]
曲芬 [2 ]
机构
[1] 河北北方学院检验学院
[2] 解放军第三〇二医院临床检验中心
关键词
丝状真菌; 基质辅助激光解析电离飞行时间质谱; 影响因素; 鉴定效果;
D O I
暂无
中图分类号
R446.5 [微生物学检验];
学科分类号
摘要
侵袭性真菌感染与免疫力低下患者的高发病率和高病死率密切相关,其早期诊治对提高患者救治率至关重要。基质辅助激光解析电离飞行时间质谱(matrix-assisted laser-desorption/ionization time of flight mass spectrometry,MALDI-TOF MS)技术通过检测真菌中固有的特异性蛋白从而实现对丝状真菌快速、准确的鉴定。本文从技术原理、标本前处理、鉴定效果及影响因素等方面对MALDI-TOF MS技术鉴定丝状真菌的研究进展作一综述。
引用
收藏
页码:171 / 175
页数:5
相关论文
共 20 条
  • [1] 丝状真菌质谱鉴定前处理方法及应用.[J].黄艳飞;常峥;白婕;朱敏;张明新;王玫;张桂;李修远;童贻刚;王景林;鲁辛辛;.中华医学杂志.2017, 30
  • [2] 质谱仪在真菌鉴定中的应用与评价
    王欢
    贾天野
    鲍春梅
    张成龙
    张鞠玲
    崔恩博
    陈素明
    徐东平
    曲芬
    [J]. 传染病信息, 2015, 28 (04) : 210 - 214
  • [3] Performance of MALDI-TOF MS platforms for fungal identification
    Cassagne, Carole
    Normand, Anne-Cecile
    L'Ollivier, Coralie
    Ranque, Stephane
    Piarroux, Renaud
    [J]. MYCOSES, 2016, 59 (11) : 678 - 690
  • [4] MALDI-TOF MS for the Diagnosis of Infectious Diseases
    Patel, Robin
    [J]. CLINICAL CHEMISTRY, 2015, 61 (01) : 100 - 111
  • [5] MALDI-TOF mass spectrometry identification of filamentous fungi in the clinical laboratory
    Ranque, Stephane
    Normand, Anne-Cecile
    Cassagne, Carole
    Murat, Jean-Benjamin
    Bourgeois, Nathalie
    Dalle, Frederic
    Gari-Toussaint, Martine
    Fourquet, Patrick
    Hendrickx, Marijke
    Piarroux, Renaud
    [J]. MYCOSES, 2014, 57 (03) : 135 - 140
  • [6] Identification of fungal microorganisms by MALDI-TOF mass spectrometry
    Chalupova, Jana
    Raus, Martin
    Sedlarova, Michaela
    Sebela, Marek
    [J]. BIOTECHNOLOGY ADVANCES, 2014, 32 (01) : 230 - 241
  • [7] MALDI-TOF mass spectrometry – a rapid method for the identification of dermatophyte species.[J].Pietro Nenoff;Marcel Erhard;Jan C. Simon;Grace K. Muylowa;Jürgen Herrmann;Waldemar Rataj;Yvonne Gräser.Medical Mycology.2013, 1
  • [8] Successful Identification of Clinical Dermatophyte and Neoscytalidium Species by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry.[J].Kinda Alshawa;Jean-Luc Beretti;Claire Lacroix;Martine Feuilhade;Brunhilde Dauphin;Gilles Quesne;Noura Hassouni;Xavier Nassif;Marie-Elisabeth Bougnoux.Journal of Clinical Microbiology.2012, 7
  • [9] MALDI-TOF MS proteomic phenotyping of filamentous and other fungi from clinical origin
    Del Chierico, Federica
    Masotti, Andrea
    Onori, Manuela
    Fiscarelli, Ersilia
    Mancinelli, Livia
    Ricciotti, Gabriella
    Alghisi, Federico
    Dimiziani, Leopoldo
    Manetti, Cesare
    Urbani, Andrea
    Muraca, Maurizio
    Putignani, Lorenza
    [J]. JOURNAL OF PROTEOMICS, 2012, 75 (11) : 3314 - 3330
  • [10] The essence on mass spectrometry based microbial diagnostics
    Kliem, Magdalena
    Sauer, Sascha
    [J]. CURRENT OPINION IN MICROBIOLOGY, 2012, 15 (03) : 397 - 402