炎症和心力衰竭

被引:23
作者
周素平
杨成明
机构
[1] 第三军医大学大坪医院野战外科研究所心内科
关键词
心力衰竭; 炎症; 细胞因子;
D O I
暂无
中图分类号
R541.6 [血液循环衰竭];
学科分类号
摘要
炎症是心血管疾病的重要方面,心力衰竭病人炎症因子常过度表达,其通过影响心肌收缩力,引起心肌肥大,诱导心肌凋亡、纤维化,促进心脏重构等作用促进心力衰竭的发生发展,而且炎症因子预示着心血管不良事件的发生。抗炎将是极有希望的治疗心力衰竭的措施。
引用
收藏
页码:493 / 496
页数:4
相关论文
共 15 条
[1]  
CYTOKINE[P]. GOMPELS URSULA;DEWIN DAVID;CATUSSE JULIE.英国专利:WO2006126025A2,2006-11-30
[2]  
Immunomodulatory effect of pentoxi-fylline in suppressing experimental autoimmune myocarditis. Takehana H,Inomata T,N iwano H,et al. C irc J . 2002
[3]  
E ffect of AT1 receptor antagonism onvascular and circulating inflammatory mediators in SHR:role of NF-kappaB/IkappaB system. Sanz-Rosa D,Oubina MP,Cediel E,et al. American Journal of Physiology Heart and Circulatory Physiology . 2005
[4]  
Therapy of ischem ic cardiomyopathy with theimmunomodulating agent heart failure. Sliwa K,AassH,Kone VN,et al. Circulation . 2004
[5]  
Immunomodulating therapy with intrave-nous immunoglobulin in patients with chronic heart failure. Gullestad L,Aass H,F jeld JG,et al. Circulation . 2001
[6]  
C-reactive protein in acute myocardialinfarction:association with heart failure. Berton G,Cordiano R,Palm ieri R,et al. American Heart Journal . 2003
[7]  
How to RECOVER from RENAISSANCE?The signifi-cance of the results ofRECOVER,RENAISSANCE,RENEWAL and ATTACH. Anker SD,Coats AJ. International Journal of Cardiology . 2002
[8]  
Atorvastatin improves left ventricularsystolic function and serum markers of inflammation in nonischem ic heart fail-ure. Sola S,Muhammad QS,Lerakis S,et al. Journal of the American College of Cardiology . 2006
[9]  
Myocarditis induced by targeted ex-pression of theMCP-1 gene in murine cardiac muscle. Kolattukudy PE,Quach T,Bergese S,et al. American Journal of Pathology . 1998
[10]  
Tumor necrosis factor-alpha andmyocardial remodeling in progression of heart failure:a current perspective. Bradham WS,Bozkurt B,Gunasinghe H,et al. Cardiovasc Respir . 2002