慢性乙肝活动期HBV复制与红细胞免疫功能变化的关系

被引：6

作者：

邓瑞莲

罗冰芬

邝慕珠

机构：

[1] 广东省东莞市石龙人民医院检验科

[2] 深圳市沙头角人民医院

来源：

中原医刊 | 2005年 / 12期

关键词：

慢性乙型肝炎; 血清HBV-DNA; 红细胞免疫粘附功能;

D O I：

暂无

中图分类号：

R512.62 [];

学科分类号：

100401 ;

摘要：

目的分析慢性乙肝活动期HBV阳性与阴性患者体内红细胞(RBC)免疫粘附功能的变化。方法收集慢性乙肝活动期患者75例、正常体检者61例,应用萤光定量PCR法(FQ-PCR)检测血清方法HBV-DNA、酵母多糖粘附RBC免疫粘附功能。结果慢性乙肝活动期患者组RBCC3b受体花环率(RCR)明显低于正常对照组(P=0.021),而RBC免疫复合物花环率(RICR)显著高于正常对照组(P=0.033)。HBV-DNA(+)组与HBV-DNA(-)组相比较,HBV-DNA(+)组RCR降低(P=0.001),差异有显著性,RICR显著升高(P=0.013)。HBV-DNA(-)组与正常对照组比较,RICR增高(P=0.004)。RICR与RCR呈负相关(r=-0.460,P=0.000)。结论慢性乙肝活动期患者RBC免疫粘附功能低下。血清HBV-DNA复制与否与慢性乙肝活动期患者RBC免疫功能密切相关。

引用

页码：21 / 22

页数：2

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