嗜麦芽寡养单胞菌耐药机制的研究

被引:21
作者
孙二琳
机构
[1] 天津市感染性疾病研究所天津
关键词
嗜麦芽寡养单胞菌; 抗生素耐药性; 固有耐药; 外排泵;
D O I
10.13461/j.cnki.cja.003144
中图分类号
R96 [药理学];
学科分类号
100602 ; 100706 ;
摘要
嗜麦芽寡养单胞菌为机会致病菌 ,已成为医院内感染的一个重要致病菌 ,该菌耐药性强 ,几乎对临床使用的抗生素都有耐药 ,对 β 内酰胺类 ,氨基糖苷类和大环内酯类固有耐药。对部分抗生素甚至高度耐药。嗜麦芽寡养单胞菌对多种抗生素和一些消毒剂表现出的抗性与其外膜渗透屏障、外排系统、各种酶类及靶位的迅速突变有关。
引用
收藏
页码:445 / 448
页数:4
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