中药抗高血压药理学研究现状与展望

被引：70

作者：

吕圭源 ^{[1
]}

苏洁 ^{[1
]}

陈素红 ^{[2
]}

机构：

[1] 浙江中医药大学药物研究所

[2] 浙江工业大学长三角绿色制药协同创新中心

来源：

中国药理学与毒理学杂志 | 2016年 / 30卷 / 12期

关键词：

高血压; 中药; 药理学; 代谢性高血压; 动物模型;

D O I：

暂无

中图分类号：

R285 [中药药理学];

学科分类号：

100806 [中药药理学];

摘要：

高血压病的发病率和增长率很高,病理病机复杂不清,严重危害人类健康。目前,高血压病无法根治,现用于治疗高血压病的化学药降压疗效显著,但需终身应用和需多药合用,也有明显不良反应,而降低高血压并发症作用不显著。中药有中医理论指导,在降压的同时能改善代谢异常,降低并发症和预后甚优,其优势或潜能尚未充分发挥,临床应用尚少。代谢性高血压已成为高血压病主体,其形成机制主要涉及代谢异常相关胰岛素抵抗和代谢性炎症等始动病理机制。系统阐述中药抗高血压药理学研究等现状、尤其代谢性高血压模型的研制与应用,对开展中药治疗高血压、尤其治愈高血压的新探索具有十分重要的意义。

引用

页码：1301 / 1311

页数：11

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