白细胞介素12在细胞免疫及抗肿瘤中的作用

被引:5
作者
杨家和
钱其军
机构
[1] 第二军医大学东方肝胆外科医院肿瘤免疫和治疗中心
[2] 第二军医大学东方肝胆外科医院肿瘤免疫和治疗中心 上海
[3] 上海
关键词
白细胞介素12; 免疫;
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
IL-12是由巨噬细胞和B细胞产生的一种二聚体细胞因子,是具有多种生物活性的免疫效应细胞生长刺激因子。细胞因子网络在维持免疫功能,促进机体抗感染方面起重要作用。特别是能促进T细胞和NK细胞的增殖与杀瘤作用,诱导IFN-γ等多种细胞因子的产生,调节Th1细胞发育,因而具有良好的抗癌作用。
引用
收藏
页码:219 / 222
页数:4
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