共 10 条
[1]
Direct antidiabetic effect of leptin through triglyceride depletion of tissues. Shimabukuro M,Koyama K,Chen G,et al. Proceedings of the National Academy of Sciences of the United States of America . 1997
[2]
Reversing adipocyte differentiation: Implications for treatment of obesity. Zhou YT,Wang ZW,Higa M,et al. Proceedings of the National Academy of Sciences of the United States of America . 1999
[3]
Correction of obesity and diabetes in genetically obese mice by leptin gene therapy. Muzzin P,Eisensmith RC,Copeland KC,et al. Proceedings of the National Academy of Sciences of the United States of America . 1996
[4]
Effect of the obese gene product on body weight regulation in ob ob mice. Pelleymounter MA,Cullen MJ,Baker MB,et al. Science . 1995
[5]
Serum immunoreactive-leptin concentrations in normal weight and obese humans. Considine RV,Sinha MK,Heiman ML,et al. The New England Journal of Medicine . 1996
[6]
Leptin gene therapy and daily protein administration: a comparative study in the ob ob mouse. Morsy MA,Gu MC,Zhao JZ,et al. Gene Therapy . 1998
[7]
Weight-reducing effects of plasma protein encoded by the obese gene. Halaas JL,Gajiwala KS,Maffei M,et al. Science . 1995
[8]
Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy. Chen G,Koyama K,Yuan X,et al. Proceedings of the National Academy of Sciences of the United States of America . 1996
[9]
An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Morsy MA,Gu M,Motzel S,et al. Proceedings of the National Academy of Sciences of the United States of America . 1998
[10]
Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin. Murphy JE,Zhou S,Giese K,et al. Proceedings of the National Academy of Sciences of the United States of America . 1997