真菌毒素对肠道屏障的影响

被引：8

作者：

潘佳雯

王楠

佟晶晶

王明阳

陈新亮

龙淼

机构：

[1] 沈阳农业大学畜牧兽医学院

来源：

动物医学进展 | 2018年 / 39卷 / 11期

关键词：

真菌毒素; 肠上皮细胞; 肠道屏障; 微生物菌群;

D O I：

10.16437/j.cnki.1007-5038.2018.11.022

中图分类号：

S859.8 [兽医毒物学];

学科分类号：

090604 [动物药学];

摘要：

存在于人类食品和畜禽饲料中的真菌毒素,尤其是脱氧雪腐镰刀菌烯醇(DON)、玉米赤霉烯酮(ZEN)、黄曲霉毒素B1(AFB1)对人类和动物健康可造成严重危害。肠黏膜层、肠黏液、肠道微生物菌群对肠道健康起到重要保护作用。了解真菌毒素如何与肠屏障相互作用,尤其是真菌毒素对肠上皮细胞、黏液和微生物菌群之间的影响,对阐明真菌毒素的毒性作用具有重要意义。论文总结了近年来3种主要真菌毒素对肠道屏障的影响,为防控真菌毒素中毒提供参考。

引用

页码：114 / 117

页数：4

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