造影剂肾病发生的临床相关因素分析

被引:8
作者
曹瑞华
叶平
刘源
机构
[1] 解放军总医院老年心血管二科
关键词
造影剂肾病; 冠状动脉造影;
D O I
暂无
中图分类号
R595.3 [药源性疾病];
学科分类号
摘要
目的探讨冠状动脉造影后发生造影剂肾病(RCIN)的临床相关因素及术前水化的作用。方法回顾性分析2006年8月至2008年8月解放军总医院住院行冠状动脉造影患者279例,其中肾功能不全者给予水化,比较临床特点、造影当日静脉液体入量和造影前后血清肌酐的变化。结果RCIN总发生率6.81%(19/279),高血压患者中RCIN发生率为8.65%(16/185),糖尿病患者中RCIN发生率为12.1%(12/99),肾功能不全患者中RCIN发病率为0。多因素Logistic回归分析显示,与发生RCIN相关的因素分别是年龄、糖尿病、造影当日静脉补液量,与性别、吸烟、高血压、冠心病、肾功能不全无关。结论60岁以上人群RCIN的发生率较高,可能与肾脏储备能力降低有关;术前充分水化是减少RCIN发生的有效办法。
引用
收藏
页码:258 / 260
页数:3
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