他汀类药物多效性的临床研究进展

被引:15
作者
徐辉
杨跃进
机构
[1] 中国医学科学院北京协和医学院心血管病研究所阜外心血管病医院
关键词
他汀; 多效性; 介入治疗; 心力衰竭; 心房颤动;
D O I
暂无
中图分类号
R96 [药理学];
学科分类号
100602 ; 100706 ;
摘要
近年来数个大规模临床研究相继证实,应用他汀类药物可明显降低血清总胆固醇和低密度脂蛋白胆固醇水平,显著降低冠心病发病率、心血管病死亡率乃至全因死亡率,从而奠定了他汀在冠心病一级、二级预防中的基石地位。然而,随着基础与临床研究的深入,越来越多的证据表明,他汀类药物具有独立于调脂作用外的多种疗效,即他汀的多效性。现将着重从循证医学的角度对他汀类药物的多效性进行综述。
引用
收藏
页码:649 / 652
页数:4
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