经颅直流电刺激介入任务导向性训练对脑卒中患者上肢功能障碍的影响

被引:16
作者
汤从智
蔡倩
杨玺
徐亮
马明
孙武东
孙悦
机构
[1] 东南大学附属中大医院康复医学科,南京
关键词
经颅直流电; 脑卒中; 阳极; 上肢; 任务导向性训练;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
100204 [神经病学];
摘要
目的观察在任务导向性训练的不同时间点(训练前和训练过程中)进行经颅直流电刺激(tDCS)对脑卒中患者上肢功能障碍的影响。方法选取符合标准的脑卒中患者90例, 采用随机数字表法将其分为A组、B组和C组, 每组患者30例, 3组患者均进行上肢任务导向性训练, A组患者在任务导向性训练前给予患侧大脑半球M1区20 min的tDCS治疗, tDCS治疗每日1次, 每次20 min, 每周治疗5 d, 连续治疗4周;B组患者在任务导向性训练的同时给予tDCS治疗, tDCS治疗部位和参数同A组;C组患者则在任务导向性训练的同时给予安慰性刺激。于治疗前和治疗4周后采用Fugl-Meyer功能评分上肢部分(FMA-UE)、偏瘫上肢功能测试-香港版(FTHUE-HK)和改良Barthel指数(MBI)分别评估3组患者的上肢运动功能、上肢功能性和实用性以及日常生活活动能力。结果治疗4周后, 3组患者的FMA-UE评分、FTHUE-HK评级和MBI评分较组内治疗前均显著提高, 差异均有统计学意义(P<0.05);治疗4周后, B组患者的FMA-UE评分、FTHUE-HK评级和MBI评分分别为(40.57±7.66)分、(4.33±0.76)级和(66.67±9.72)分, 显著优于A组和C组治疗4周后, 差异均有统计学意义(P<0.05)。结论 tDCS联合任务导向性训练可显著改善脑卒中患者的上肢运动功能和日常生活活动能力, 且在任务训练的同时进行tDCS疗效更佳。
引用
收藏
相关论文
共 30 条
[1]
Optimal Combination of Anodal Transcranial Direct Current Stimulations and Motor Imagery Interventions.[J].Elodie Saruco;Franck Di Rienzo;Susana Nunez-Nagy;Miguel A. Rubio-Gonzalez;Ursula Debarnot;Christian Collet;Aymeric Guillot;Arnaud Saimpont;Nicole Wenderoth.Neural Plasticity.2018,
[2]
Polarity specific effects of transcranial direct current stimulation on interhemispheric inhibition..[J].Toshiki Tazoe;Takashi Endoh;Taku Kitamura;Toru Ogata.PLoS ONE.2017, 12
[3]
Nerve Stimulation Enhances Task-Oriented Training in Chronic; Severe Motor Deficit After Stroke: A Randomized Trial.[J].Cheryl Carrico;Kenneth C. Chelette;Philip M. Westgate;Elizabeth Powell;Laurie Nichols;Anne Fleischer;Lumy Sawaki.Stroke.2016,
[4]
The Homeostatic Interaction Between Anodal Transcranial Direct Current Stimulation and Motor Learning in Humans is Related to GABAA Activity [J].
Amadi, Ugwechi ;
Allman, Claire ;
Johansen-Berg, Heidi ;
Stagg, Charlotte J. .
BRAIN STIMULATION, 2015, 8 (05) :898-905
[5]
tDCS-enhanced motor and cognitive function in neurological diseases.[J].Agnes Flöel.NeuroImage.2014,
[6]
Timing-dependent priming effects of tDCS on ankle motor skill learning.[J].Aishwarya Sriraman;Tatsuya Oishi;Sangeetha Madhavan.Brain Research.2014,
[7]
Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases.[J].Min-Fang Kuo;Walter Paulus;Michael A. Nitsche.NeuroImage.2014,
[8]
Transcranial Direct Current Stimulation (tDCS) Relieved Itching in a Patient With Chronic Neuropathic Pain [J].
Knotkova, Helena ;
Portenoy, Russell K. ;
Cruciani, Ricardo A. .
CLINICAL JOURNAL OF PAIN, 2013, 29 (07) :621-622
[9]
Transcranial direct current stimulation (tDCS) and robotic practice in chronic stroke: The dimension of timing [J].
Giacobbe, V. ;
Krebs, H. I. ;
Volpe, B. T. ;
Pascual-Leone, A. ;
Rykman, A. ;
Zeiarati, G. ;
Fregni, F. ;
Dipietro, L. ;
Thickbroom, G. W. ;
Edwards, D. J. .
NEUROREHABILITATION, 2013, 33 (01) :49-56
[10]
Impact of tDCS on performance and learning of target detection: Interaction with stimulus characteristics and experimental design [J].
Coffman, B. A. ;
Trumbo, M. C. ;
Flores, R. A. ;
Garcia, C. M. ;
van der Merwe, A. J. ;
Wassermann, E. M. ;
Weisend, M. P. ;
Clark, V. P. .
NEUROPSYCHOLOGIA, 2012, 50 (07) :1594-1602