单核/巨噬细胞及其趋化因子与脑缺血再灌注损伤

被引:9
作者
李力仙
戴黎萌
江涛
戴钦舜
机构
[1] 哈尔滨医科大学附属第一医院神经外科
[2] 北京市神经外科研究所
关键词
单核/巨噬细胞; 趋化因子; 脑缺血; 再灌注;
D O I
暂无
中图分类号
R743.02 [];
学科分类号
1002 ;
摘要
缺血再灌注能诱导脑组织表达单核细胞趋化因子 1(MCP 1)和巨噬细胞炎性蛋白 1(MIP 1) ,并伴有单核 /巨噬细胞的浸润和激活。一方面 ,这些趋化因子的表达和单核 /巨噬细胞的激活有助于增强机体抵抗力 ,参与组织修复 ,是机体防御反应的重要组成部分 ;另一方面 ,又可加重组织损伤。文章论述了单核 /巨噬细胞及其趋化因子MCP 1和MIP 1在脑缺血再灌注损伤中的作用
引用
收藏
页码:89 / 91
页数:3
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