综述脑卒中后抑郁发病机制的研究进展

被引：35

作者：

湛清扬 ^{[1
]}

孔繁一 ^{[2
]}

吕亚男 ^{[1
]}

赵慧怡 ^{[3
]}

黄树明 ^{[1
]}

张博 ^{[1
]}

机构：

[1] 黑龙江中医药大学中医药研究院

[2] 哈尔滨医科大学附属第一医院神经外科

[3] 黑龙江中医药大学

来源：

中风与神经疾病杂志 | 2022年 / 39卷 / 04期

关键词：

脑卒中后抑郁; 发病机制; 神经递质; 5-羟色胺; 抑郁;

D O I：

10.19845/j.cnki.zfysjjbzz.2022.0096

中图分类号：

R743.3 [急性脑血管疾病（中风）]; R749.4 [情感性精神病];

学科分类号：

100204 [神经病学];

摘要：

<正>脑卒中是造成第三位全球人类死亡的原因，多数研究者更关注脑卒中后运动功能障碍，但脑卒中后患者的认知和情绪等方面也受到不同程度的损害，主要表现为精力不足、睡眠障碍、兴趣降低、被动、悲观甚至自杀。大约20%的脑卒中幸存者在12个月的随访中发展为抑郁症[1],并且脑卒中后抑郁(post-stroke depression, PSD)患者在10 y内死亡的可能性是脑卒中后无抑郁的3.4倍。所有脑卒中病例中，缺血性脑卒中占87%,

引用

页码：369 / 371

页数：3

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