针刺对血管性痴呆患者尿中氧化应激标志物的影响

被引:9
作者
刘存志 [1 ,2 ]
石广霞 [1 ]
黄玉兰 [1 ]
朱虹 [3 ]
王麟鹏 [1 ]
机构
[1] 首都医科大学附属北京中医医院针灸中心
[2] 天津中医药大学第一附属医院
[3] 天津市天拖医院
关键词
针刺; 氧化应激; 标志物; 血管性痴呆; 简易精神状态检查;
D O I
暂无
中图分类号
R246.6 [神经精神病科];
学科分类号
100225 [精神医学];
摘要
目的探讨氧化应激与血管性痴呆(VD)的关系以及针刺的抗氧化作用机制。方法通过对16例VD患者的观察,分析针刺前后简易精神状态检查(MMSE)分值和尿中氧化应激标志物8-羟基脱氧鸟苷(8-OHdG)、8-异前列腺素(8-isoPGF2α)以及硝基酪氨酸(NT)水平的变化。结果针刺后VD患者MMSE分值较针刺前明显提高,尿中8-OHdG含量明显下降,而尿中8-isoPGF2α和NT含量未见明显变化。结论针刺可降低VD患者DNA氧化损伤标志物8-OHdG的水平,发挥抗氧化作用,改善VD患者的认知功能。
引用
收藏
页码:18 / 20
页数:3
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