脑源性神经营养因子与抑郁障碍相关性研究的进展

被引:3
作者
孙喜蓉
秦虹云
机构
[1] 上海市浦东新区精神卫生中心
关键词
脑源性神经营养因子; 抑郁障碍; 相关研究; 综述;
D O I
10.13342/j.cnki.cjhp.2011.10.051
中图分类号
R749.4 [情感性精神病];
学科分类号
100205 ;
摘要
本文综述了国内外关于抑郁障碍与脑源性神经营养因子(BDNF)相关性的研究进展,并从抑郁障碍患者脑内和血清BDNF浓度、抗抑郁剂对抑郁患者脑内BDNF浓度的影响、抑郁患者BDNF下降的机制和BDNF下降与认知功能的关系等方面做了详尽阐述。
引用
收藏
页码:1276 / 1278
页数:3
相关论文
共 11 条
[1]   抑郁症患者血清BDNF水平与相关因素分析 [J].
李晓照 ;
陈泽奇 ;
胡随瑜 ;
张宏耕 .
中国临床心理学杂志, 2005, (03) :312-313+342
[2]   抗抑郁剂对慢性应激小鼠海马神经元再生的影响 [J].
李云峰 ;
刘艳芹 ;
张有志 ;
袁莉 ;
罗质璞 .
中国药理学通报, 2004, (04) :385-388
[3]   Effects of paroxetine or milnacipran on serum brain-derived neurotrophic factor in depressed patients [J].
Yoshimura, Reiji ;
Mitoma, Masae ;
Sugita, Atsuko ;
Hori, Hikaru ;
Okamoto, Tatsuya ;
Umene, Wakako ;
Ueda, Nobuhisa ;
Nakamura, Jun .
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2007, 31 (05) :1034-1037
[4]   A neurotrophic model for stress-related mood disorders [J].
Duman, Ronald S. ;
Monteggia, Lisa M. .
BIOLOGICAL PSYCHIATRY, 2006, 59 (12) :1116-1127
[5]   Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity [J].
Karege, F ;
Bondolfi, G ;
Gervasoni, N ;
Schwald, M ;
Aubry, JM ;
Bertschy, G .
BIOLOGICAL PSYCHIATRY, 2005, 57 (09) :1068-1072
[6]  
Physiology of BDNF: focus on hypothalamic function[J] . Lucia Tapia-Arancibia,Florence Rage,Laurent Givalois,Sandor Arancibia.Frontiers in Neuroendocrinology . 2004 (2)
[7]   Critical role of brain-derived neurotrophic factor in mood disorders [J].
Hashimoto, K ;
Shimizu, E ;
Iyo, M .
BRAIN RESEARCH REVIEWS, 2004, 45 (02) :104-114
[8]   Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants [J].
Shimizu, E ;
Hashimoto, K ;
Okamura, N ;
Koike, K ;
Komatsu, N ;
Kumakiri, C ;
Nakazato, M ;
Watanabe, H ;
Shinoda, N ;
Okada, S ;
Iyo, M .
BIOLOGICAL PSYCHIATRY, 2003, 54 (01) :70-75
[9]  
Brain-derived neurotrophic factor: a bridge between major depression and Alzheimer’s disease?[J] . Shih-Jen Tsai.Medical Hypotheses . 2003 (1)
[10]   Decreased serum brain-derived neurotrophic factor levels in major depressed patients [J].
Karege, F ;
Perret, G ;
Bondolfi, G ;
Schwald, M ;
Bertschy, G ;
Aubry, JM .
PSYCHIATRY RESEARCH, 2002, 109 (02) :143-148