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Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis
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Major role for amphotericin B-flucytosine combination in severe cryptococcosis. Dromer F,Bernede-Bauduin C,Guillemot D, et al. PloS ONE . 2008
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Nonsense andmissense mutations in FCY2 and FCY1 genes are responsi-ble for flucytosine resistance and flucytosine-fluconazolecross-resistance in clinical isolates of Candida lusitaniae. Florent M,Nol T,Ruprich-Robert G,et al. Antimicrobial Agents and Chemotherapy . 2009
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Mutational analysis of flucytosineresistance in Candida glabrata. Edlind T D,Katiyar S K. Antimicrobial Agents and Chemotherapy . 2010
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Fluconazole for the management of invasive candidiasis:where do we stand after15years. Charlier C,Hart E,Lefort A,et al. Journal of Antimicrobial Chemotherapy . 2006
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Surface response modeling to examine the combination of amphotericin B deoxycholate and 5-fluorocytosine for treatment of invasive candidiasis. Hope WW,Warn PA,Sharp A, et al. The Journal of Infectious Diseases . 2005
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Functionalcharacterization of the Chlamydomonas reinhardtii ERG3 or-tholog,a gene involved in the biosynthesis of ergosterol. Brumfield K M,Moroney J V,Moore T S,et al. PLoS One . 2010
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Identification andcharacterization of four azole-resistant erg3 mutants of Can-dida albicans. Martel C M,Parker J E,Bader O,et al. Antimicrobial Agents and Chemotherapy . 2010
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Overexpression of Candi-da albicans CDR1,CDR2,or MDR1 does not produce sig-nificant changes in echinocandin susceptibility. Niimi K,Maki K,Ikeda F,et al. Antimicrobial Agents and Chemotherapy . 2006