同型半胱氨酸与颈动脉粥样硬化关系的探讨

被引:3
作者
张顺开
胡永启
易兴阳
泮光强
黄毅
泮建豹
不详
机构
[1] 温州医学院附属第三医院
[2] 温州医学院附属第三医院 瑞安
[3] 瑞安
[4] 瑞安
关键词
同型半胱氨酸; 颈动脉疾病; 脑梗死; 动脉粥样硬化;
D O I
暂无
中图分类号
R743 [脑血管疾病];
学科分类号
摘要
目的 探讨同型半胱氨酸(Hcy)与颈动脉粥样硬化的关系。方法 对208例脑梗死患者与50例健康对照者采用高效液相色谱分析法进行Hcy水平的测定,并对脑梗死患者采用彩色多普勒超声进行颈动脉检测。结果 208例脑梗死患者94例患高Hcy血症,占45.2%,平均血浆Hcy浓度19.6±8.2μmol/L,显著高于对照组10.1±3.1μmol/L(P<0.01)。94例高Hcy血症脑梗死患者发生颈动脉粥样硬化85例,轻度14例,中度46例,重度25例;颈动脉狭窄程度轻度16例,中度46例,重度23例;而114例正常Hcy脑梗死患者发生颈A粥样硬化89例,轻度42例,中度32例,重度15例,颈动脉狭窄程度轻度47例,中度31例,重度11例。结论 同型半胱氨酸可能参与脑卒中的发病,高Hcy血症患者颈动脉粥样硬化发生率高,以中、重型居多,且多有颈动脉中、重度狭窄。
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页码:3 / 4
页数:2
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