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- [7] Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD .2 J Seiderer,I Elben,J Diegelmann,J Glas,J Stallhofer,C Tillack. Inflamm Bowel Dis . 2008