C反应蛋白测定在慢性阻塞性肺病急性加重期的临床意义

被引:17
作者
石慧芳
陈山
何海武
机构
[1] 海南省农垦总局医院呼吸内科
关键词
C反应蛋白; 慢性阻塞性肺病; 急性加重期;
D O I
暂无
中图分类号
R563.9 [其他];
学科分类号
1002 ; 100201 ;
摘要
目的探讨C反应蛋白(CRP)测定在慢性阻塞性肺病(COPD)急性加重期诊治中的临床意义。方法选择COPD急性加重住院患者79例,比较其治疗前后血清CRP水平、白细胞总数(WBC)和肺功能(FEV1%预计值)动态变化情况。结果血清CRP和WBC水平在急性加重期较正常组显著升高(P<0.01)、治疗缓解组较治疗前明显降低(P<0.01),未缓解组血清CRP水平无明显变化、WBC较治疗前明显降低(P<0.05)。治疗前和未缓解组血清CRP阳性率明显高于WBC(P<0.001),缓解组CRP阳性率明显低于WBC(P<0.05);结论血清CRP测定可作为评价COPD急性加重期患者感染的客观指标,优于WBC等指标,可作为治疗效果评判的重要标志物。
引用
收藏
页码:1448 / 1450
页数:3
相关论文
共 7 条
[1]  
Changes and significance of leptin in induced sputoum of patients with chronic obstructive pulmonary disease. WU XM,LI JH,LI CM. China Journal of Chinese Materia Medica . 2007
[2]  
Chronic Obstructive Pulmonary Disease Giagnosis Guide. Chin J Tubrec Respir Dis . 2002
[3]  
Therapeutic effect of nebulizations of ventolin oxygen inhalation on acute exacerbations of chronic obstructive pulmonary disease. CHEN XH. Journal of Chinese Medicine Research . 2005
[4]  
C-reactive protein:A clinical marker in community acquired pneumonia. SMITH RP,LIPWORTH BJ,GREE IA,et al. Chest . 1995
[5]  
C-reactive protein level and the correlationbetween lung function and CRP levels in patients with chronic obstructive pulmonary disease. WU SJ,CHEN P. J Cent South Univ(Med Sci) . 2005
[6]  
C-reactive protein in simple community-acquired pneumonia. Smith RP,Lipworth BJ. Chest . 1995
[7]  
Systemic and upper and lower airway inflammation at exacerbation of chronic obstructive pulmonary disease. Hurst JR,Perera WR,Wilkinson TM,et al. American Journal of Respiratory and Critical Care Medicine . 2006