骨钙素的能量代谢调节作用

被引：9

作者：

盛彤

郭翔宇

王新祥

谢培凤

商学征

周晖

关菘

龚雁冰

王颖

机构：

[1] 北京中医药大学东方医院内分泌代谢科

来源：

中华内分泌代谢杂志 | 2014年 / 30卷 / 10期

关键词：

骨钙素; 成骨细胞; 肥胖症;

D O I：

暂无

中图分类号：

R589.2 [脂肪代谢障碍]; R587.1 [糖尿病];

学科分类号：

100201 [内科学];

摘要：

成骨细胞分泌的骨钙素是反映成骨细胞活性的敏感而特异的指标。近年的研究还发现,骨钙素是骨骼内分泌功能的重要媒介。羧化不全骨钙素可以促进胰岛β细胞增殖和胰岛素分泌,降低血糖和血脂水平,表明骨钙素对能量代谢具有重要的调控作用,这一发现将为肥胖症和糖尿病等代谢性疾病的治疗提供新的思路。

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