乳腺癌保乳手术切缘安全范围的分子病理学研究

被引:1
作者
黄世勇 [1 ]
黄传胜 [2 ]
梁运龙 [1 ]
机构
[1] 广东省阳江市人民医院病理科
[2] 广东省阳春市人民医院病理科
关键词
保乳手术; 手术切缘; 安全范围; 分子病理学;
D O I
暂无
中图分类号
R737.9 [乳腺肿瘤];
学科分类号
100214 ;
摘要
目的通过检测肿瘤周边浸润及周围组织的癌变规律,找出病理检查难以发现的隐性癌灶范围,为临床医生决策保乳手术切除边缘得出依据。方法各手术部位切除标本分别行HE染色、分子生物学检测和免疫组化。结果癌旁1cm及2cm处阳性因素比例高于3cm处(P<0.05),lcm与2cm处之间差异无统计学意义(P>0.05)。结论原发性乳腺癌C-erbB-2扩增和P53突变患者行保乳手术应扩大切除范围>2cm,以减少局部复发的危险。
引用
收藏
页码:6 / 7
页数:2
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