血必净联合血液灌流治疗急性百草枯中毒临床疗效分析

被引：5

作者：

王晓梅

施阳

董芸

代将

王一凡

机构：

[1] 四川省人民医院急救中心

来源：

四川医学 | 2011年 / 32卷 / 06期

关键词：

百草枯; 中毒; 血必净; 血液灌流;

D O I：

10.16252/j.cnki.issn1004-0501-2011.06.023

中图分类号：

R595.4 [药物中毒];

学科分类号：

1002 ; 100201 ;

摘要：

目的总结分析血必净联合血液灌流治疗急性百草枯中毒的临床疗效。方法以我院2007年6月～2010年6月收治的急性重度百草枯中毒患者57例为研究对象,根据治疗方案分为单纯灌流组和联合治疗组,单纯灌流组为常规急救治疗基础上应用血液灌流;联合治疗组在单纯灌流组的基础上联合应用血必净注射液治疗。结果两组患者治疗后血清ALT、AST、CK、CKMB、LDH、Cr水平显著下降,血清炎性因子CRP、MDA、TNF-α水平显著降低,SOD活性显著升高,以联合治疗组显著。单纯灌流组死亡16例,治愈12例;联合治疗组死亡9例,治愈20例,联合治疗组病死率显著低于单纯灌流组(=3.944,P=0.047)。结论血必净联合血液灌流可降低百草枯对重要脏器的损害、降低炎性因子水平,提高治愈率。

引用

页码：817 / 819

页数：3

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