血管紧张素转化酶抑制肽的研究进展

被引:47
作者
何海伦
陈秀兰
孙彩云
张玉忠
机构
[1] 山东大学微生物技术国家重点实验室
关键词
降压肽; 血管紧张素转化酶(ACE); 血管紧张素转化酶抑制剂;
D O I
10.13523/j.cb.20040903
中图分类号
R544.1 [高血压];
学科分类号
摘要
血管紧张素转化酶 (angiotensin I convertingenzyme ,ACE)在血压调节方面起着重要的作用 ,当其受到抑制时血压就会降低。许多合成的ACE抑制剂被广泛地应用于临床 ,但会造成多种副作用。近年来 ,对天然ACE抑制肽的研究表明 ,一些来源于蛋白酶解产生的活性肽可以对ACE起到有效的抑制作用。综述了血管紧张素转化酶的抑制肽的降压原理 ,种类和来源以及结构特点等的研究进展 ,并对其应用前景进行了展望
引用
收藏
页码:7 / 11
页数:5
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