老年男性动脉硬化血压波动与脑梗死发生的关系

被引:4
作者
方根强
顾祎
郝长宁
韩丽
黄震浩
石一沁
张琳琳
黄燕超
段俊丽
机构
[1] 上海交通大学医学院附属新华医院老年医学科
关键词
老年人; 血压; 血压波动; 脑梗死; 数学方法;
D O I
暂无
中图分类号
R544.1 [高血压];
学科分类号
摘要
目的探讨血压波动对老年男性脑梗死发生的影响。方法 1527例患有动脉硬化的老年(年龄>65岁)男性患者,所有患者监测动态血压,根据有无脑梗死将入选患者分为2组:脑梗死组(607例)和非脑梗死组(920例),用数学平滑曲线方法先将每一个体24 h血压数据进行分析,再描绘出一条适合个体血压变化趋势的曲线,计算实际血压值与该趋势曲线相应位置所形成差值的标准差即为血压波动值,然后比较2组血压波动的情况。结果脑梗死组中24 h的收缩压波动值明显高于非脑梗死组[(8.4±2.2)与(8.0±2.0)mm Hg,t=-2.909,P<0.01];其中白昼收缩压血压波动明显升高[(8.2±2.2)与(7.8±2.1)mm Hg,t=-2.969,P<0.01];而夜间收缩压波动2组差异无统计学意义[(8.9±3.9)与(8.7±3.7)mm Hg,P>0.05];各阶段舒张期血压波动差异无统计学意义[24 h舒张压波动值(5.5±3.8)与(5.5±1.5)mm Hg,P>0.05;白昼舒张压波动值(5.4±1.5)与(5.3±1.4)mm Hg,P>0.05;夜间舒张压波动值(6.1±2.7)与(6.1±2.6)mm Hg,P>0.05]。结论在老年男性动脉硬化相关疾病患者中,脑梗死的发生与白昼收缩压的波动密切相关,而与夜间收缩压和舒张压波动无关。
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