非编码RNA在骨代谢及骨重建中作用的研究进展

被引：12

作者：

黄竹

杨岚

江千舟

郭吕华

机构：

[1] 广州医科大学附属口腔医院广州口腔疾病研究所广州医科大学口腔医学重点实验室

来源：

实用医学杂志 | 2020年 / 36卷 / 03期

关键词：

非编码RNA; 骨代谢; 骨重建;

D O I：

暂无

中图分类号：

R68 [骨科学（运动系疾病、矫形外科学）];

学科分类号：

100220 [骨科学];

摘要：

非编码RNA(non-coding RNAs,ncRNAs)是一类不编码蛋白质的RNA分子,占据了人类基因组的大部分。研究发现,非编码RNA与成骨分化及骨代谢关系密切。目前,许多与骨相关疾病发病机制尚未明了。因此,本文重点介绍了三种常见非编码RNA(微小RNA,长链非编码RNA和环状RNA)的分类,作用机制,对骨生长分化、骨代谢的影响,以及对骨相关疾病的影响等方面。

引用

页码：420 / 424

页数：5

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