基因编辑在农业动物中的应用进展

被引:10
作者
马宇浩 [1 ]
高爽 [2 ]
董向会 [2 ]
李瑞 [2 ]
邓学梅 [1 ]
机构
[1] 中国农业大学动物科学技术学院动物遗传资源与分子育种实验室
[2] 内蒙古草原金峰畜牧有限公司
关键词
基因编辑; 农业动物; 研究进展;
D O I
暂无
中图分类号
S813.3 [生物技术遗传育种];
学科分类号
071007 ; 090501 ;
摘要
基因编辑技术是对生物体内源基因精确修饰的一项技术,从出现到应用,对农业科学的发展起到了极大的推动作用。现代基因编辑技术发展分为三个主要阶段:锌指核酸酶(zinc finger nuclease,ZFN)阶段、类转录激活效应因子核酸酶(transcription activation-like effector nuclease, TALEN)阶段和成簇的规律间隔短回文重复序列(clustered regularly interspaced short palindromic repeats,CRISPR)阶段。基因编辑技术具有特异性识别靶点序列,定点修饰靶向基因的特点,该技术应用于农业动物关键性状主效基因的验证,并通过对已知功能基因的精准编辑加快农业动物的育种进程。本文将对基因编辑及在农业动物中的应用情况进行综述,为动物育种和相关领域的研究提供参考。
引用
收藏
页码:2230 / 2239
页数:10
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