乳腺癌新辅助化疗的研究进展

被引:21
作者
沈雷
张宏伟
机构
[1] 复旦大学附属中山医院普外科
关键词
乳腺癌; 新辅助化疗; 化疗方案; 病理完全缓解;
D O I
暂无
中图分类号
R737.9 [乳腺肿瘤];
学科分类号
100214 [肿瘤学];
摘要
近年,乳腺癌新辅助化疗的研究不再局限于局部晚期乳腺癌、炎性乳腺癌或肿块较大不可保乳的乳腺癌患者,研究的范围进一步扩大到可手术的早期乳腺癌,这得益于进一步认识到新辅助化疗的优势。新辅助化疗不仅提高了保乳率,更便于了解患者对化疗方案的敏感性,甚至预测患者的预后,从而指导临床化疗方案的调整。本文将对新辅助化疗药物的选择、疗程及用法等方面进行总结,同时对病理完全缓解的定义、预后意义与分子分型的关系等内容进行探讨。
引用
收藏
页码:244 / 248
页数:5
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[3]
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[4]
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[5]
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[6]
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