载药纳米微粒的应用及研究进展

被引：26

作者：

吴新荣

机构：

[1] 广州军区广州总医院广东广州

来源：

中国医院药学杂志 | 2001年 / 03期

关键词：

纳米; 载药微粒; 控释制剂; 靶向给药;

D O I：

暂无

中图分类号：

R944 [剂型];

学科分类号：

100702 [药剂学];

摘要：

目的:对纳米、纳米科技及其在药物研究中的应用进行介绍。方法:通过对国内外文献的总结,概述了载药纳米微粒中的普通载药微粒、控释载药微粒、靶向定位载药微粒、载药磁性微粒等类别。介绍了复乳化法技术、超声乳化法、等电临界法、氧化还原法等制备载药纳米微粒的方法。结果:纳米技术与现代医药学结合的产物——载药纳米微粒具有易吸收、定向性强等优点。结论:载药纳米微粒的研究开发可解决口服易水解药物的给药途径,延长药物的体内半衰期,更精确的靶向定位给药,减少药物不良反应,消除生物屏障对药物作用的影响。

引用

页数：3

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