勺型形态高龄高血压患者的动态动脉硬化指数与靶器官损伤关系

被引:5
作者
郭瑞敏 [1 ]
李英梅 [1 ]
刘欣艳 [1 ]
杨根妹 [1 ]
刘宗军 [2 ]
金惠根 [2 ]
韩敏 [1 ]
余雪君 [1 ]
机构
[1] 上海中医药大学附属普陀医院老年科
[2] 上海中医药大学附属普陀医院心内科
关键词
动态动脉硬化指数; 动脉硬化; 动态血压; 高血压; 勺型曲线;
D O I
10.19428/j.cnki.sjpm.2013.06.023
中图分类号
R544.1 [高血压];
学科分类号
100201 [内科学];
摘要
[目的]亚临床靶器官损伤代表着心血管疾病发展的中间阶段。本研究通过测试动态动脉硬化指数(ambulatory arterial stiffness index,AASI),在高龄高血压患者中,探讨靶器官损伤和AASI相关性。[方法]收集本院老年科住院96例高龄(≥80岁)高血压患者资料,根据24 h动态血压勺型形态分为勺型曲线组(40例)和非勺型曲线组(56例),进行AASI测定,评估AASI、平均脉压与内生肌酐清除率、颈动脉内膜厚度、左室重量、左室重量指数之间的关系。[结果]通过测试AASI发现:①在所有高龄高血压患者中,24 h尿蛋白定量与AASI呈独立正相关(P<0.05)。②在勺型曲线高血压患者中,IMT与AASI呈独立正相关(P<0.01)。[结论]考虑高血压患者血压昼夜变化、勺型曲线的影响,AASI在评估靶器官损伤中具有一定的诊断价值。
引用
收藏
页码:345 / 348
页数:4
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