非酒精性脂肪性肝病与代谢综合征

被引：36

作者：

高鑫

机构：

[1] 复旦大学附属中山医院内分泌科

来源：

中国实用内科杂志 | 2011年 / 31卷 / 09期

关键词：

非酒精性脂肪性肝病; 代谢综合征; 胰岛素抵抗; 2型糖尿病; 心血管疾病;

D O I：

暂无

中图分类号：

R575.5 [肝代谢障碍]; R589 [代谢病];

学科分类号：

1002 ; 100201 ;

摘要：

非酒精性脂肪性肝病(NAFLD)事实上是一个肝脏脂肪性病变的疾病谱,包括单纯性脂肪肝、非酒精性脂肪性肝炎(NASH)、肝纤维化或肝硬化、肝衰竭,甚至部分患者发生肝细胞性肝癌。NAFLD与代谢综合征(MS)密切伴随,并认为是代谢综合征的肝脏表现。胰岛素抵抗可能是二者共同的发病基础。NAFLD已经成为MS、2型糖尿病(T2DM)和心血管疾病(CVD)的重要的独立预测因子,NAFLD成为T2DM和CVD高危人群,因此早期诊断和早期干预NAFLD对预防T2DM和CVD具有重要意义。

引用

页码：664 / 667

页数：4

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