内质网应激与帕金森病

被引：23

作者：

王晟东

白洁

机构：

[1] 昆明理工大学生物工程技术研究中心

来源：

生命科学 | 2010年 / 22卷 / 04期

关键词：

内质网应激; 未折叠蛋白应答; 帕金森病;

D O I：

10.13376/j.cbls/2010.04.015

中图分类号：

R742.5 [震颤麻痹综合征];

学科分类号：

100204 [神经病学];

摘要：

内质网是细胞内最重要的细胞器之一,内质网功能与细胞状态密切相关。异常蛋白在内质网的堆积、胆固醇代谢异常、钙代谢紊乱等均能引起内质网应激。内质网应激在细胞生理病理中发挥重要作用。研究表明:内质网应激与神经退行性疾病,如帕金森病密切相关。该文简单概述了内质网应激与帕金森病之间的关系。

引用

页码：326 / 330

页数：5

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