激活素-抑制素-卵泡抑素系统研究进展

被引:25
作者
陈颖
徐苓
机构
[1] 中国医学科学院中国协和医科大学北京协和医院妇产科
关键词
激活素; 抑制素; 卵泡抑素; 女性生殖;
D O I
暂无
中图分类号
R33 [人体生理学];
学科分类号
100123 [人体微生态学];
摘要
抑制素、激活素和卵泡抑素主要由垂体细胞和卵巢颗粒细胞分泌,是细胞转化生长因子-β超家族的成员。通过内分泌及自/旁分泌调节作用参与了女性体内众多的生殖生理活动。本文综述关于抑制素、激活素和卵泡抑素的研究进展,包括生物合成、信号传导的调节、生理作用机制,在女性生殖生理中的重要作用及其相关临床研究及应用。
引用
收藏
页码:288 / 292
页数:5
相关论文
共 9 条
[1]
血清抑制素水平在体外受精-胚胎移植超排卵周期中预测卵巢反应性的价值 [J].
陈颖 ;
郁琦 ;
张以文 ;
何方方 ;
孙正怡 .
中华妇产科杂志, 2006, (06) :368-371
[2]
Follicular arrest in polycystic ovary syndrome is associated with deficient inhibin A and B biosynthesis [J].
Welt, CK ;
Taylor, AE ;
Fox, J ;
Messerlian, GM ;
Adams, JM ;
Schneyer, AL .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (10) :5582-5587
[3]
Regulation of gonadotropins by inhibin and activin [J].
Gregory, SJ ;
Kaiser, UB .
SEMINARS IN REPRODUCTIVE MEDICINE, 2004, 22 (03) :253-267
[4]
Role of activin A as a mediator of in vitro endometrial stromal cell decidualization via the cyclic adenosine monophosphate pathway.[J].Emily P Tierney;Linda C Giudice.Fertility and Sterility.2004,
[5]
Inhibins and activins in pregnancy.[J].P. Florio;S. Luisi;P. Ciarmela;F.M. Severi;C. Bocchi;F. Petraglia.Molecular and Cellular Endocrinology.2004, 1
[6]
Activins, inhibins, and follistatins: From endocrinology to signaling. A paradigm for the new millennium [J].
Welt, C ;
Sidis, Y ;
Keutmann, H ;
Schneyer, A .
EXPERIMENTAL BIOLOGY AND MEDICINE, 2002, 227 (09) :724-752
[7]
Inhibins/activins as diagnostic markers for ovarian cancer [J].
Robertson, DM ;
Stephenson, T ;
Pruysers, E ;
Burger, HG ;
McCloud, P ;
Tsigos, A ;
Groome, N ;
Mamers, P ;
McNeilage, J ;
Jobling, T ;
Healy, D .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2002, 191 (01) :97-103
[8]
Activin Stimulates Proliferation of Rat Ovarian Thecal-Interstitial Cells<sup>1</sup>.[J].Antoni J. Duleba;Tugce Pehlivan;Rocco Carbone;Robert Z. Spaczynski.Biology of Reproduction.2001, 3
[9]
Women with declining ovarian reserve may demonstrate a decrease in day 3 serum inhibin B before a rise in day 3 follicle-stimulating hormone [J].
Seifer, DB ;
Scott, RT ;
Bergh, PA ;
Arbogast, LK ;
Friedman, CI ;
Mack, CK ;
Danforth, DR .
FERTILITY AND STERILITY, 1999, 72 (01) :63-65