正常和局部脑缺血时猫脑微血管、软脑膜血管和Willis环血管中缩胆囊肽、神经肽Y和降钙素基因相关肽含量的研究

被引:3
作者
徐超
杨春莲
杜莉芬
周荣
朱凌
郑肖钊
范子体
王叶
机构
[1] 北京市神经外科研究所
[2] 中日友好医院临床医学研究所
关键词
缩胆囊素; 神经肽 Y; 脑动脉; 降钙素基因相关肽;
D O I
暂无
中图分类号
学科分类号
摘要
研究了正常猫脑微血管,软脑膜血管和 Willis 环血管内缩胆囊肽(CCK)、神经肽 Y(NPY)和降钙素基因关肽(CGRP)各自的含量谱型。结果表明软脑膜血管和 Willis 环血管有相似的谱型,而脑微血管中三肽呈另一谱型。每种肽在三种血管中的谱型都不相同。猫 MCA 阻断后,脑微血管中 CCK 含量明显下降,而二种大血管中 CCK 明显升高。三种血管中 NPY 均轻度下降。二种大血管中 CGRP 明显下降,而脑微血管中 CGRP 无甚变化。
引用
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页码:51 / 54+92
页数:5
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