重症监护病房非白色念珠菌和白色念珠菌感染危险因素的比较

被引：4

作者：

黄磊 ^{[1
]}

赵令玺 ^{[2
]}

张卫星 ^{[1
]}

罗华 ^{[1
]}

陈映群 ^{[1
]}

张声 ^{[1
]}

机构：

[1] 北京大学深圳医院ICU

[2] 江西省南丰县人民医院外科

来源：

中国医师进修杂志 | 2010年 / 19期

关键词：

念珠菌,白色; 危险因素; 重症监护病房;

D O I：

暂无

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

目的研究重症监护病房(ICU)患者非白色念珠菌和白色念珠菌感染危险因素的差异。方法回顾性分析2003年2月至2009年4月ICU获得性念珠菌感染患者103例,其中非白色念珠菌感染46例,白色念珠菌感染57例,对其多个危险因素进行统计学分析。结果非白色念珠菌中,光滑念珠菌19例(18.4%),近平滑念珠菌13例(12.6%),热带念珠菌10例(9.7%),克柔念珠菌2例(1.9%),其他念珠菌2例(1.9%)。经Logistic多因素回归分析发现,中心静脉导管(CVC)留置>2 d(OR=32.477,95%可信区间:4.905～215.035,P=0.000)、全胃肠外营养(OR=3.119,95%可信区间:1.214～8.015,P=0.018)和氟康唑预防治疗(OR=5.084,95%可信区间:1.319～19.596,P=0.018)与非白色念珠菌感染密切相关。结论 CVC留置>2 d、全胃肠外营养和氟康唑预防治疗是非白色念珠菌感染的独立危险因素,可用于指导经验性抗真菌治疗的药物选择。

引用

页码：6 / 9

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