葡萄籽原花青素及维生素E对氧化应激仔猪生长性能、血清氧化还原状态和肝脏氧化损伤的影响

被引：21

作者：

赵娇

周招洪

梁小芳

毛湘冰

陈代文

余冰

机构：

[1] 四川农业大学动物营养研究所/教育部动物抗病营养重点实验室

来源：

中国农业科学 | 2013年 / 19期

关键词：

葡萄籽原花青素; 维生素E; 断奶仔猪; 氧化应激; 肝脏;

D O I：

暂无

中图分类号：

S828.5 [];

学科分类号：

090502 ;

摘要：

【目的】研究饲粮添加葡萄籽原花青素(grape seed procyanidins,GSPs)和维生素E(vitamin E,VE)对氧化应激仔猪生长性能、血清氧化还原状态及肝脏氧化损伤的影响。【方法】24头28 d的断奶仔猪(L×Y),随机分为4组,每组6个重复,每个重复1头猪。NC组和Diqaut组饲喂基础饲粮,GSPs+Diquat组和VE+Diquat组分别饲喂在基础饲粮中添加100 mg·kg-1GSPs和50 mg·kg-1VE的试验饲粮。在试验第10 d对Diquat组、GSPs+Diquat组和VE+Diquat组试猪腹腔注射Diquat(10 mg·kg-1),NC组注射生理盐水。试验期为17 d。【结果】结果显示,与NC组相比,注射Diquat导致仔猪生长性能,血清和肝脏抗氧化能力以及肝脏ALT和AST活性显著降低(P<0.05),血清ALT和AST活性显著升高(P<0.05);饲粮添加100 mg·kg-1GSPs或50 mg·kg-1VE均显著改善应激仔猪血清GSH-px活性和抗能力及肝脏ALT和AST活性(P<0.05),降低血清ALT、AST活性和MDA含量(P<0.05)。与此同时,GSPs还显著增加仔猪血清SOD活性、抗·OH能力及肝脏T-AOC和抗·OH能力(P<0.05),降低肝脏MDA含量(P<0.05)。【结论】饲粮添加100 mg·kg-1GSPs或50 mg·kg-1VE均能有效缓解Diquat所致仔猪氧化应激,且在血清和肝脏抗氧化方面GSPs效果较好。

引用

页码：4157 / 4164

页数：8

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