组蛋白去甲基化酶研究进展

被引:26
作者
徐龙勇
陈德桂
机构
[1] 中国科学院上海生命科学研究院生物化学与细胞生物学研究所
关键词
组蛋白去甲基化酶; 生理功能; 组蛋白甲基化; 表观遗传学;
D O I
10.13376/j.cbls/2010.02.015
中图分类号
R341 [];
学科分类号
摘要
组蛋白甲基化是一种重要的表观遗传修饰方式,2004年组蛋白去甲基化酶的发现使人们认识到组蛋白的甲基化也是一个可逆的修饰过程,并由此掀起了人们对组蛋白去甲基化研究的热潮。该文主要从近年来研究人员在组蛋白去甲基化酶的鉴定、组蛋白去甲基化酶的功能研究等方面取得的进展进行阐述,并就该方面的研究进行展望。
引用
收藏
页码:109 / 114
页数:6
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