2型糖尿病患者大脑中动脉狭窄的危险因素分析

被引：20

作者：

林健雯

G.Neil Thomas

黄如训

方燕南

黄家星

机构：

[1] 香港中文大学威尔斯亲王医院内科及药物治疗学系,香港中文大学威尔斯亲王医院内科及药物治疗学系,中山大学附属第一医院神经科,中山大学附属第一医院神经科,香港中文大学威尔斯亲王医院内科及药物治疗学系现在中山大学附属第一医院神经科

来源：

中华神经科杂志 | 2004年 / 02期

关键词：

糖尿病,非胰岛素依赖型; 大脑中动脉; 脑动脉疾病;

D O I：

暂无

中图分类号：

R587.1 [糖尿病];

学科分类号：

1002 ; 100201 ;

摘要：

目的　探讨 2型糖尿病患者大脑中动脉 (MCA)狭窄的危险因素。方法　对 2 2 0 2例 2型糖尿病患者用经颅多普勒 (TCD)筛选 ,MCA狭窄者为病例组 ,其余为对照组 ,行年龄、性别、糖尿病病程的频率配对后分析MCA狭窄的危险因素。结果　MCA狭窄组与对照组在高血压 (76 8%与5 3 4 % )、抗高血压治疗 (5 1 5 %与 2 6 6 % )、收缩压 [14 7与 138mmHg(1mmHg =0 133kPa) ]、舒张压(81与 84mmHg)、血糖 (8 1与 8 7mmol/L)、白蛋白尿 (4 1 1%与 30 1% )、尿的白蛋白肌酐比 (ACR)(5 9与 3 5mg/mmol)、低密度脂蛋白 (LDL) (3 8与 3 6mmol/L)的分布差异存在显著意义。Logistic回归发现年龄、高血压、LDL 胆固醇是MCA狭窄的独立危险因素。结论　年龄增长、高血压、LDL 胆固醇高是MCA狭窄的危险因素。

引用

页码：41 / 44

页数：4

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