5羟色胺在肠易激综合征中的作用

[1] Serotonin-transporter polymorphism pharmaco-genetics in diarrhea-predominant irritable bowel syn-drome. CAMILLERI M,ATANASOVA E,CARLSON P J,et al. Gastroenterology . 2002

[2] Effect ofrenzapride on transit in constipation-predominant irri-table bowel syndrome. CAMILLERI M,MCKINZIE S,FOX J,et al. Clin Gastroenterol Hepa-tol . 2004

[3] Serotonintransporter gene olymorphismin irritable bowel syn-drome. PATA C,ERDAL M E,DERICI E,et al. The American journal of Gastroenterology . 2002

[4] Enterochromaffin cells and 5-HT signaling in thepathophysiology of disorders of gastrointestinal func-tion. CROWELL M D,SHETZLINE M A,MOSES P L,etal. Current Opinion in Investigational Drugs . 2004

[5] Irritable bowel syndrome:newagents targeting serotonin receptor subtypes. DE PONTI F,TONINI M. Drugs . 2001

[6] Effect of a novel 5-HT3receptor agonist MKC-733 on upper gastrointestinal motility in humans. COLEMAN N S,MARCIANI L,BLACKSHAW E,et al. Ali mentary Pharmacol Ther . 2003

[7] The 5-HT3receptor antagonist alosetron inhibits thecolorectal distention induced depressor response andspinal c-fos expression in the anaesthetised rat. KOZLOWSKI C M,GREEN A,GRUNDY D,et al. Gut . 2000

[8] Compliance,tone and sensitivity of the rectumindifferent subtypes of irritable bowel syndrome. STEENS J,VANDER SCHAAR P J,PENNING C,etal. Neurogastroenterology and Motility . 2002

[9] Pa-tients with constipation-predominant irritable bowelsyndrome(IBS)may have elevated serotonin concen-trations in colonic mucosa as compared with diarrhea-predominant patients and subjects with normal bowelhabits. MI WAJ,ECHIZEN H,MATSUEDA K,et al. Digestion . 2001

[10] Associationbetween a functional polymorphism in the serotonintransporter gene and diarrhoea predominant irritablebowel syndrome in women. YEO A,BOYD P,LUMSDEN S,et al. Gut . 2004

[1] Serotonin-transporter polymorphism pharmaco-genetics in diarrhea-predominant irritable bowel syn-drome. CAMILLERI M,ATANASOVA E,CARLSON P J,et al. Gastroenterology . 2002

[2] Effect ofrenzapride on transit in constipation-predominant irri-table bowel syndrome. CAMILLERI M,MCKINZIE S,FOX J,et al. Clin Gastroenterol Hepa-tol . 2004

[3] Serotonintransporter gene olymorphismin irritable bowel syn-drome. PATA C,ERDAL M E,DERICI E,et al. The American journal of Gastroenterology . 2002

[4] Enterochromaffin cells and 5-HT signaling in thepathophysiology of disorders of gastrointestinal func-tion. CROWELL M D,SHETZLINE M A,MOSES P L,etal. Current Opinion in Investigational Drugs . 2004

[5] Irritable bowel syndrome:newagents targeting serotonin receptor subtypes. DE PONTI F,TONINI M. Drugs . 2001

[6] Effect of a novel 5-HT3receptor agonist MKC-733 on upper gastrointestinal motility in humans. COLEMAN N S,MARCIANI L,BLACKSHAW E,et al. Ali mentary Pharmacol Ther . 2003

[7] The 5-HT3receptor antagonist alosetron inhibits thecolorectal distention induced depressor response andspinal c-fos expression in the anaesthetised rat. KOZLOWSKI C M,GREEN A,GRUNDY D,et al. Gut . 2000

[8] Compliance,tone and sensitivity of the rectumindifferent subtypes of irritable bowel syndrome. STEENS J,VANDER SCHAAR P J,PENNING C,etal. Neurogastroenterology and Motility . 2002

[9] Pa-tients with constipation-predominant irritable bowelsyndrome(IBS)may have elevated serotonin concen-trations in colonic mucosa as compared with diarrhea-predominant patients and subjects with normal bowelhabits. MI WAJ,ECHIZEN H,MATSUEDA K,et al. Digestion . 2001

[10] Associationbetween a functional polymorphism in the serotonintransporter gene and diarrhoea predominant irritablebowel syndrome in women. YEO A,BOYD P,LUMSDEN S,et al. Gut . 2004