Th22细胞及其细胞因子在银屑病发病机制中的作用

被引：6

作者：

辛甜甜 ^{[1
,2
]}

王晓华 ^{[2
]}

陈永锋 ^{[1
]}

机构：

[1] 广东省皮肤性病防治中心

[2] 广东医学院

来源：

皮肤性病诊疗学杂志 | 2012年 / 19卷 / 04期

基金：

广东省科技计划;

关键词：

Th22; 银屑病;

D O I：

暂无

中图分类号：

R758.63 [牛皮癣（银屑病）];

学科分类号：

100206 ;

摘要：

银屑病是一种由T细胞介导的疾病,以表皮过度增殖、角质形成细胞异常分化伴血管增生及皮损处免疫细胞浸润为特征。近来发现了一群独立于Th1、Th2及Th17细胞的新型CD4+记忆性T细胞——Th22细胞,其在银屑病等一些炎症性皮肤病中不同程度升高,使免疫调节机制进一步完善,通过了解其作用机理或许可开展将其作为一个治疗银屑病的新型靶点的研究。本文就Th22细胞及其细胞因子在银屑病中的作用机制进行综述。

引用

页码：257 / 259+266 +266

页数：4

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