99Tcm-ECDSPECT无创性脑血流量测定

被引:4
作者
杨仪
刘增礼
唐军
田金玲
陆文栋
机构
[1] 苏州大学附属第二医院核医学科
关键词
99Tcm-ECD; SPECT; 脑血流;
D O I
暂无
中图分类号
R817.4 [在诊断上的应用];
学科分类号
1001 ; 100105 ; 100207 ; 100602 ;
摘要
建立了一种使用99Tcm-ECD为显像剂,SPECT为显像装置,不抽血定量测定局部脑血流的方法。两个不同年龄组正常志愿者共20例,通过静脉弹丸式注射99Tcm-ECD,利用动态显像和感兴趣区勾画技术获取大脑半球及主动脉弓的时间放射性曲线,同时对曲线进行死时间校正,结合图形分析方法确立脑血流灌注率(Ku),大脑半球的灌注指数(BPI)获得平均脑血流量(mCBF)。结果显示:20例正常人的脑血流值分别为53.81±5.27 mL(100 g)-1.min-1(5~16岁),47.19±4.99 mL(100 g)-1.min-1(22~32岁),不同年龄组间有显著差异。本测定方法具有无创性,实际工作中的可操作性等特点,在临床上便于广泛开展,有一定应用价值。
引用
收藏
页码:94 / 97
页数:4
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