围手术期急性心肌梗死患者乳酸和乳酸清除率水平研究

被引:9
作者
高洁 [1 ,2 ]
张京岚 [1 ,2 ]
叶清 [1 ,2 ]
陈峣 [1 ,2 ]
机构
[1] 首都医科大学附属北京安贞医院
[2] 北京市心肺血管疾病研究所综合监护室
关键词
乳酸; 乳酸清除率; 急性心肌梗死; 围手术期;
D O I
暂无
中图分类号
R542.22 [];
学科分类号
摘要
目的:通过冠心病患者术后早期动脉血乳酸水平及乳酸清除率,评价其对围术期急性心肌梗死(perioperative acute myocardial infarction,PAMI)的发病、预后的提示作用。方法:入选2010年1月至2012年3月,入住我院SICU的冠心病患者,比较其中确诊为围术期PAMI的35例患者,及围术期平稳过渡的31例患者,动脉乳酸值及血乳酸清除率进行回顾性分析。结果:研究显示,PAMI患者初始乳酸水平(3.05±1.18)mmol/L较非心肌梗死患者(1.70±0.79)mmol/L明显增高,而6 h乳酸水平分别为心肌梗死组(2.10±0.89)mmol/L非心肌梗死组(0.96±0.41)mmol/L,差异具有统计学意义(P<0.05),心肌梗死患者中初始乳酸水平在KillipⅠ、Ⅱ级(2.24±0.88)mmol/L及KillipⅢ、Ⅳ级(3.89±1.45)mmol/L之间,差异有统计学意义(P<0.05),而患者术后心肌梗死乳酸清除率则无明显减少,显示乳酸清除率不能明确提示PAMI发生概率上升。结论:乳酸测量可作为ICU医师对PAMI的另一有效的预警指标。
引用
收藏
页码:713 / 715
页数:3
相关论文
共 9 条
[1]
舒芬太尼与芬太尼对小儿心脏手术乳酸水平影响的回顾性研究 [J].
欧阳川 ;
王学勇 ;
张晶 ;
刘亚光 ;
李书闻 ;
卿恩明 .
心肺血管病杂志, 2010, 29 (02) :132-135
[2]
动态监测血乳酸对先天性心脏病心内直视手术患儿的临床意义 [J].
李瑞兰 ;
任晓莉 .
心肺血管病杂志, 2007, (03) :174-175
[3]
Blood lactate monitoring in critically ill patients: A systematic health technology assessment [J].
Jansen, Tim C. ;
van Bommel, Jasper ;
Bakker, Jan .
CRITICAL CARE MEDICINE, 2009, 37 (10) :2827-2839
[4]
Prognostic role of insulin resistance as assessed by homeostatic model assessment index in the acute phase of myocardial infarction in nondiabetic patients submitted to percutaneous coronary intervention [J].
Lazzeri, Chiara ;
Sori, Andrea ;
Chiostri, Marco ;
Gensini, Gian Franco ;
Valente, Serafina .
EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2009, 26 (10) :856-862
[5]
Analysis of the outcome for patients experiencing myocardial infarction and cardiopulmonary resuscitation refractory to conventional therapies necessitating extracorporeal life support rescue [J].
Chen, JS ;
Ko, WJ ;
Yu, HY ;
Lai, LP ;
Huang, SC ;
Chi, NH ;
Tsai, CH ;
Wang, SS ;
Lin, FY ;
Chen, YS .
CRITICAL CARE MEDICINE, 2006, 34 (04) :950-957
[6]
Prognosis of patients who develop acute renal failure during the first 24 hours of cardiogenic shock after myocardial infarction [J].
Koreny, M ;
Delle Karth, G ;
Geppert, A ;
Neunteufl, T ;
Priglinger, U ;
Heinz, G ;
Siostrzonek, P .
AMERICAN JOURNAL OF MEDICINE, 2002, 112 (02) :115-119
[7]
Comparison of lactate or BE during out-of-hospital cardiac arrest to determine metabolic acidosis [J].
Prause, G ;
Ratzenhofer-Comenda, B ;
Smolle-Jüttner, F ;
Heydar-Fadai, J ;
Wildner, G ;
Spernbauer, P ;
Smolle, J ;
Hetz, H .
RESUSCITATION, 2001, 51 (03) :297-300
[8]
Effects of cardiogenic shock on lactate and glucose metabolism after heart surgery [J].
Chioléro, RL ;
Revelly, JP ;
Leverve, X ;
Gersbach, P ;
Cayeux, MC ;
Berger, MM ;
Tappy, L .
CRITICAL CARE MEDICINE, 2000, 28 (12) :3784-3791
[9]
MYOCARDIAL LACTATE METABOLISM - EVIDENCE OF LACTATE RELEASE DURING NET CHEMICAL-EXTRACTION IN MAN [J].
GERTZ, EW ;
WISNESKI, JA ;
NEESE, R ;
BRISTOW, JD ;
SEARLE, GL ;
HANLON, JT .
CIRCULATION, 1981, 63 (06) :1273-1279