SICU严重脓毒症患者血降钙素原和乳酸清除率的临床分析

被引:1
作者
叶华 [1 ]
李莉 [2 ]
钟贵芳 [1 ]
张克林 [1 ]
郭瑞莲 [1 ]
程慧华 [1 ]
何清 [1 ]
机构
[1] 中山大学孙逸仙纪念医院SICU
[2] 中山大学孙逸仙纪念医院急诊科
基金
广东省自然科学基金;
关键词
严重脓毒症; 血清降钙素原; 早期乳酸清除率;
D O I
暂无
中图分类号
R459.7 [急症、急救处理];
学科分类号
100218 ;
摘要
目的探讨血清降钙素原(PCT)及乳酸清除在SICU严重脓毒症患者中的临床价值。方法研究对象来源于我院SICU从2013年6月至2015年5月收治的78例严重脓毒症患者。临床数据包括血清降钙素原、APACHEⅡ评分、6 h动脉血乳酸清除率及患者预后等相关资料。根据临床结局及动脉血乳酸水平,所有患者分为存活组(n=54)和死亡组(n=24);高乳酸清除率组(n=51)和低乳酸清除率组(n=27)。结果各组年龄、性别、APACHEⅡ评分和基础血乳酸值差异无显著性意义。死亡组患者的血清PCT水平明显高于存活组(P<0.05),死亡组6 h乳酸清除率较存活组明显低(P<0.05)。无论死亡组和存活组,PCT水平与患者乳酸清除率均无相关关系(r2=0.189,P>0.05;r2=0.133,P>0.05)。结论严重脓毒症患者血清降钙素原水平升高及乳酸清除能力降低,二者水平变化间没有相关性。
引用
收藏
页码:707 / 710
页数:4
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